Polynucleotides are a modern biostimulatory approach in aesthetic medicine, designed to support the skin’s natural renewal mechanisms. They do not function as fillers and do not provide immediate volume, but are used in protocols aimed at the gradual improvement of skin quality.
The science behind the treatment
Polynucleotides are purified DNA fragments, often derived from salmonid fish, which have been studied for their role in tissue healing and regeneration. In aesthetic medicine, they are used as biostimulatory agents that support skin renewal.
Their action appears to be linked to mechanisms involved in cellular repair, improved hydration, and the reduction of local inflammatory responses. Results are not immediate but develop gradually over the course of treatment.
Triple action
- Collagen biostimulation
- May support the natural production of collagen and contribute to improved skin elasticity.
- Hydration improvement
- May enhance the feeling of deeper hydration and contribute to a healthier-looking complexion.
- Anti-inflammatory support
- May help reduce local sensitivity and improve the overall appearance of the skin.




